Chemotherapeutic Drugs Interfere With Which of the Following

True The fluoroquinolones disrupt DNA replication and repair by targeting which two enzymes. Each oral chemotherapeutic was also evaluated for its effects on coumarin-containing products and its potential to prolong the QTc interval.


Chemotherapy Drugs

D It specifically inhibits the cell division cycle in rapidly dividing cells.

. We evaluated the effects on the MG63 OS cell line when TMQ 5-fluorouracil and oxaliplatin combinations were applied. QUESTION 5 Which of the following would not be a reasonable therapeutic strategy for chemotherapy. The most effective drugs that treat infections caused by flukes tapeworms and roundworms eradicate the adult stages of the organisms.

A condition in which there is an extreme loss of white blood cells is known as chronic anemia. C 29 29 Drug resistance occurs A because bacteria are normal microbiota. The disruption of mitosis implies that these drugs are active specifically during the M phase of the cell cycle.

Compare risks and benefits of common medications used for Neutropenia Associated with Chemotherapy. Amphotericin B and polymyxin interfere with cell wall synthesis protein synthesis cell membrane function DNA function The penicillin stable in gastric acid and suitable for oral administration is methicillin carbenicillin closacillin pencillin-G The most selective antibiotics are those that interfere with the synthesis of bacterial DNA. Cell- cycle specific chemotherapy drugs cannot differentiate healthy from cancerous cells thus adverse effects are seen.

The following side effects are common occurring in greater than 30 for patients taking Vincristine. Oral chemotherapeutics were also analyzed for interactions with acid suppressor medications such as proton-pump inhibitors PPIs histamine 2-receptor antagonists H2RAs and antacids. The best and most correct answer among the choices provided by your question is the fifth choice or letter E.

These chemotherapeutics bind to the tubulin and lead to the disruption of the mitotic spindle apparatus. As such cardiology providers must be aware of potential drug-drug interactions in prescribing antiplatelet therapy in the setting of oncologic treatments Table 3. Find the most popular drugs view ratings and user reviews.

The major phase I liver CYP450 enzyme is CYP3A4 which is responsible for metabolizing more than 35 of chemotherapy drugs2 CYP3A4 enzyme activation during chemotherapy will reduce the half-life of the drug thereby decreasing. Precursors pyrimidine and purine analogs which interfere with the process of DNA synthesis and ribonucleotide reductase inhibitors which reduce production of deoxyribonucleotides. C against antibiotics and not against synthetic chemotherapeutic agents.

Anticoagulation in the oncologic setting can be. Typically block metabolism at all stages of the life cycle rather than eradicate the adult worm. The chemotherapeutic agents that attach side chains to the proteins within the cancer cells and interfere with their functions are called a.

In a recent study the drug sanguinarine demonstrated a strong activity against gram-positive and gram-negative bacteria while streptomycin was active against gram-negative strains and EDTA had only bacteriostatic activity. Nausea vomiting diarrhea Anorexia nausea diarrhea. The drug that would be most desirable has the ability to interfere with rapidly dividing cells.

9-11 In most cases an alternative P2Y12 inhibitor can be used to avoid PK interactions with specific chemotherapeutic agents. Which of the following side effects occur as a result of chemotherapy affecting the skin and the linings of the mouth throat stomach and intestines. This means for example that some CCS drugs may interfere with DNA synthesis while other CCS drugs may prevent mitosis or cell division.

Hair loss in 20-70 of patients may be partial or complete hair loss. Use of immunosuppressant drugs inhibition of caspase activity and apoptosis inhibition of growth factor synthesis interfere with DNA replication interfere with the formation of microtubules interfere with breaking down of microtubules. Just like pharmaceutical drugs certain botanicals and supplements activate or inhibit the CYP450 liver enzyme.

Interestingly the three-drug combination strongly reduced almost all the strains studied as well as the effective doses needed. Chemotherapy drugs that affect cells when they are at rest are called cell-cycle non-specific. Thank you for posting your question here in Brainly.

B It does not interfere with metabolically active cells. C It specifically inhibits cells entering G0. B when antibiotics are used indiscriminately.

A It is safe enough to prevent all apoptosis. Drugs such as methotrexate that interfere with vital cellular functions by mimicking compounds in cells are called ____. D when antibiotics are taken after the symptoms disappear.

As their name suggests they are effective at different parts of the cell cycle. E All of the answers are correct. Cell cycle specific CCS drugs are often used in cancer treatment.

The nurse uses many precautions during IV administration of vesicant chemotherapeutic agents primarily to prevent If a patient with cancer is receiving a combination of chemotherapeutic agents that is known to interfere with bone marrow they should give special attention to. Methotrexate prevents synthesis of DNA and RNA by inhibiting the production of nucleic acids. Check interactions and set up your own personal medication records.

Isolation and chemical characterization lead to the currently used chemotherapy drugs. Which of the following characteristics would be most important for a chemotherapeutic drug designed to treat cancer cells. The goal of this study was to determine the effect of TMQ in combination with chemotherapy drugs on the growth inhibition of osteosarcoma and the potential clinical utility of TMQ in the treatment of OS.

I hope my answer has come to your help. Vincristine vinblastine and vinorelbine. Antibacterial drugs that inhibit nucleic acid synthesis are not as selectively toxic as drugs that target other bacterial processes.

Angiogenesis inhibitors do not harm most normal dividing cells because they directly attack cancer cells. The following list of medications are in some way related to or used in the treatment of this condition. The scheduling of chemotherapy is set based on the type of cells rate at.


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